Inherited mutations of ion channel subunits can lead to disease but also give insight into the precise contribution of ion channels to normal physiology. Discuss for a particular ion channel family (e.g. Na+ channels, K+channels or Ca2+ channels),with reference to specific examples, how such mutations lead to neurological disease and what we learn from this about the functions of these ion channels. - Life Sciences bibliographies - in Harvard style

In-text: (Adams et al., 2010)

Your Bibliography: Adams, P., Rungta, R., Garcia, E., van den Maagdenberg, A., MacVicar, B. and Snutch, T., 2010. Contribution of calcium-dependent facilitation to synaptic plasticity revealed by migraine mutations in the P/Q-type calcium channel. Proceedings of the National Academy of Sciences, 107(43), pp.18694-18699.

In-text: (Ducros, 2014)

Your Bibliography: Ducros, A., 2014. Familial hemiplegic migraine: A model for the genetic studies of migraine. Cephalalgia, 34(13), pp.1035-1037.

In-text: (Ophoff et al., 1996)

Your Bibliography: Ophoff, R., Terwindt, G., Vergouwe, M., van Eijk, R., Oefner, P., Hoffman, S., Lamerdin, J., Mohrenweiser, H., Bulman, D., Ferrari, M., Haan, J., Lindhout, D., van Ommen, G., Hofker, M., Ferrari, M. and Frants, R., 1996. Familial Hemiplegic Migraine and Episodic Ataxia Type-2 Are Caused by Mutations in the Ca2+ Channel Gene CACNL1A4. Cell, 87(3), pp.543-552.

In-text: (Salvi et al., 2014)

Your Bibliography: Salvi, J., Bertaso, F., Mausset-Bonnefont, A., Metz, A., Lemmers, C., Ango, F., Fagni, L., Lory, P. and Mezghrani, A., 2014. RNAi silencing of P/Q-type calcium channels in Purkinje neurons of adult mouse leads to episodic ataxia type 2. Neurobiology of Disease, 68, pp.47-56.

In-text: (van den Maagdenberg et al., 2010)

Your Bibliography: van den Maagdenberg, A., Pizzorusso, T., Kaja, S., Terpolilli, N., Shapovalova, M., Hoebeek, F., Barrett, C., Gherardini, L., van de Ven, R., Todorov, B., Broos, L., Tottene, A., Gao, Z., Fodor, M., De Zeeuw, C., Frants, R., Plesnila, N., Plomp, J., Pietrobon, D. and Ferrari, M., 2010. High cortical spreading depression susceptibility and migraine-associated symptoms in Ca v 2.1 S218L mice. Annals of Neurology, 67(1), pp.85-98.

In-text: (van den Maagdenberg et al., 2010)

Your Bibliography: van den Maagdenberg, A., Pizzorusso, T., Kaja, S., Terpolilli, N., Shapovalova, M., Hoebeek, F., Barrett, C., Gherardini, L., van de Ven, R., Todorov, B., Broos, L., Tottene, A., Gao, Z., Fodor, M., De Zeeuw, C., Frants, R., Plesnila, N., Plomp, J., Pietrobon, D. and Ferrari, M., 2010. High cortical spreading depression susceptibility and migraine-associated symptoms in Ca v 2.1 S218L mice. Annals of Neurology, 67(1), pp.85-98.

In-text: (Viggiano et al., 2011)

Your Bibliography: Viggiano, A., Viggiano, E., Valentino, I., Monda, M., Viggiano, A. and De Luca, B., 2011. Cortical spreading depression affects reactive oxygen species production. Brain Research, 1368, pp.11-18.